Delayed radiation-induced lumbosacral radiculoplexus neuropathy – a diagnostic dilemma

Diabetic and non-diabetic lumbosacral radiculoplexus neuropathy.

BACKGROUND Lumbosacral radiculoplexus neuropathy (LRPN) originally described in diabetic patients is a distinct clinical condition characterized by debilitating pain, weakness and atrophy most commonly affecting the proximal thigh muscles asymmetrically. The syndrome is usually monophasic and preceded by significant weight loss (at least more than 10 lbs). Though a self-limited condition, recov...

Elevated cerebrospinal fluid protein in diabetic lumbosacral radiculoplexus neuropathy.

An 86-year-old ex-sailor with Type 2 diabetes was admitted in September 2010, with a 3-year history of weakness and pain in his legs, ataxia, recurrent falls, significant difficulties in walking and getting up, intermittent paraesthesia in his feet with strong jerks in the lower limbs and unintentional weight loss of 4 stones over the last few years. He was an ex-smoker and had previous history...

Non-diabetic lumbosacral radiculoplexus neuropathy: natural history, outcome and comparison with the diabetic variety.

Diabetic lumbosacral radiculoplexus neuropathy (DLSRPN) (other names include diabetic amyotrophy) is well recognized, unlike the non-diabetic lumbosacral radiculoplexus neuropathy (LSRPN), which has received less attention. Our objective was to characterize the natural history and outcome of LSRPN and to assess whether it is similar to the diabetic variety in its symptoms, course, electrophysio...

Organophosphate-Induced Delayed Neuropathy

Organophosphate induced delayed neuropathy.

A 19 year young male who consumed organophosphorous compound and required assisted mechanical ventilation for two weeks, later on developed delayed neuropathy is described.